Tetrahydropalmatine: Orchestrating survival – Regulating autophagy and apoptosis via the PI3K/AKT/mTOR pathway in perforator flaps

Author:

Chen Xuankuai,Fu Kejian,Lai Yingying,Dong Chengji,Chen Zhuliu,Huang Yingying,Li Guangyao,Jiang Renhao,Wu Hongqiang,Wang Anyuan,Huang Shaojie,Shen Liyan,Gao Weiyang,Li Shi

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Wenzhou Municipal Science and Technology Bureau

Science and Technology Plan Project of Wenzhou Municipality

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference62 articles.

1. On-skin biosensors for noninvasive monitoring of postoperative free flaps and replanted digits;Wu;Sci. Transl. Med,2023

2. Perforator-based cross midline flaps of the trunk: a paradigm shift in flap design;Angrigiani;Plast. Reconstr. Surg.,2023

3. Butylphthalide inhibits autophagy and promotes multiterritory perforator flap survival;Li;Front Pharm.,2020

4. Diallyl trisulfide enhances the survival of multiterritory perforator skin flaps;Dong;Front Pharm.,2022

5. Melatonin improved the survival of multi-territory perforator flaps by promoting angiogenesis and inhibiting apoptosis via the NRF2/FUNDC1 axis;Huang;Front Pharm.,2022

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