Design and synthesis of dabigatran etexilate derivatives with inhibiting thrombin activity for hepatocellular carcinoma treatment-Reference-Cited by-同舟云学术

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Design and synthesis of dabigatran etexilate derivatives with inhibiting thrombin activity for hepatocellular carcinoma treatment

Published:2024-01 Issue: Volume:170 Page:116018
ISSN:0753-3322
Container-title:Biomedicine & Pharmacotherapy
language:en
Short-container-title:Biomedicine & Pharmacotherapy

Author:

Xie Zhuo-song,Han Xiao-yang,Zhou Zi-ying,Li Si-yan,Zhu Jiang-yi,Zhang Lei,Xue Si-tu

Funder

National Natural Science Foundation of China

Chinese Academy of Meteorological Sciences

Key Research and Development Program of Zhejiang Province

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference28 articles.

1. Exosite binding in thrombin: a global structural/dynamic overview of complexes with aptamers and other ligands;Troisi;Int. J. Mol. Sci.,2021

2. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships;Bode;Protein Sci.,1992

3. New fundamentals in hemostasis;Versteeg;Physiol. Rev.,2013

4. Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis;Mackman;Arterioscler. Thromb. Vasc. Biol.,2007

5. An overview of the structure and function of thrombin;Davie;Semin Thromb. Hemost.,2006

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