NAT2 phenotype alters pharmacokinetics of rivaroxaban in healthy volunteers

Author:

Villapalos-García Gonzalo,Zubiaur Pablo,Ochoa Dolores,Soria-Chacartegui Paula,Navares-Gómez Marcos,Matas Miriam,Mejía-Abril Gina,Casajús-Rey Ana,Campodónico Diana,Román Manuel,Martín-Vílchez Samuel,Candau-Ramos Carmen,Aldama-Martín Marina,Abad-Santos FranciscoORCID

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference40 articles.

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2. Agencia Española del Medicamento y Productos Sanitarios (AEMPS). Xarelto drug label [Internet]. [cited 2023 Mar 13]. Available from: 〈https://cima.aemps.es/cima/dochtml/ft/08472018/FT_08472018.html〉.

3. In Vitro Metabolism of Rivaroxaban, an Oral, Direct Factor Xa Inhibitor, in Liver Microsomes and Hepatocytes of Rats, Dogs, and Humans;Lang;Drug Metab. Dispos.,2009

4. Therapeutic Drug Monitoring of Direct Oral Anticoagulants May Increase Their Benefit-Risk Ratio;Bernier;J. Cardiovasc Pharm.,2020

5. The myths behind DOAC measurement: Analyses of prescribing information from different regulatory bodies and a call for harmonization;Gosselin;J. Thromb. Haemost.,2022

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