Nuclear localization of P-glycoprotein is responsible for protection of the nucleus from doxorubicin in the resistant LoVo cell line

Author:

Szaflarski Witold,Sujka-Kordowska Patrycja,Januchowski Radosław,Wojtowicz Karolina,Andrzejewska Małgorzata,Nowicki Michał,Zabel Maciej

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference20 articles.

1. Function and frustration of multi-drug ABC exporter protein and design of model proteins for drug delivery using protein hydration thermodynamics;Urry;Curr Pharm Des,2009

2. Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes;Hsu;J Biol Chem,1989

3. The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein;Ueda;Biochem Biophys Res Commun,1986

4. Inhibitors of N-glycosylation as a potential tool for analysis of the mechanism of action and cellular localisation of glycoprotein P;Wojtowicz;Acta Biochim Pol,2012

5. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues;Thiebaut;Proc Natl Acad Sci U S A,1987

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