Thymoquinone, an active constituent of Nigella sativa seeds, binds with bilirubin and protects mice from hyperbilirubinemia and cyclophosphamide-induced hepatotoxicity

Author:

Laskar Amaj A.,Khan Masood A.,Rahmani Arshad H.,Fatima Sana,Younus HinaORCID

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference40 articles.

1. Bilirubin in clinical practice: a review;Fevery;Liver Int.,2008

2. Hepatic Transport and Bile Secretion;Vanstapel,1993

3. On the structure of albumin-bound bilirubin. Selective binding of intramolecularly hydrogen-bonded conformational enantiomers;Lightner;J. Biol. Chem.,1986

4. Albumin-bilirubin binding mechanism;Jacobsen;J. Biol. Chem.,1983

5. Binding of bilirubin with albumin-coupled liposomes: implications in the treatment of jaundice;Masood;Biochim. Biophys. Acta,2002

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