Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells-Reference-Cited by-同舟云学术

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Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells

Published:2017-04 Issue: Volume:135 Page:154-163
ISSN:0300-9084
Container-title:Biochimie
language:en
Short-container-title:Biochimie

Author:

Mohamad Fairus A.K.,Choudhary B.,Hosahalli S.,Kavitha N.,Shatrah O.

Funder

Ministry of Higher Education, Malaysia

University of Malaya

UMRG

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference63 articles.

1. Profiling of dihydroorotate dehydrogenase, p38 and JAK inhibitors in the rat adjuvant-induced arthritis model: a translational study;Balague;Br. J. Pharmacol.,2012

2. Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoa;Carrey;Reproduction,2002

3. Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structures;McLean;Bioorg. Med. Chem. Lett.,2010

4. Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase;Hurt;Bioorg. Med. Chem. Lett.,2006

5. Dihydroorotate dehydrogenase inhibitor A771726 (leflunomide) induces apoptosis and diminishes proliferation of multiple myeloma cells;Baumann;Mol. Cancer Ther.,2009

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