Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster”

Author:

Salvador Guilherme H.M.,dos Santos Juliana I.,Lomonte BrunoORCID,Fontes Marcos R.M.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conselho Nacional de Desenvolvimento Científico e Tecnológico

CAPES

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference58 articles.

1. Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action;Montecucco;Cell Mol. Life Sci.,2008

2. Snake venom Lys49 myotoxins: from phospholipases A2 to non-enzymatic membrane disruptors;Lomonte;Toxicon,2012

3. Phospholipase A2-a structural review;Arni;Toxicon,1996

4. Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes;Kini;Toxicon,2003

5. A new class of phospholipases A2 with lysine in place of aspartate 49. Functional consequences for calcium and substrate binding;Maraganore;J. Biol. Chem.,1984

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