A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners

Author:

Yablokov Evgeniy O.,Sushko Tatsiana A.,Ershov Pavel V.,Florinskaya Anna V.,Gnedenko Oksana V.,Shkel Tatsiana V.,Grabovec Irina P.,Strushkevich Natallia V.,Kaluzhskiy Leonid A.,Usanov Sergey A.,Gilep Andrei A.,Ivanov Alexis S.

Funder

State Academies of Sciences Fundamental Scientifc Research Program

Russian Foundation for Basic Research

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference76 articles.

1. Function of human cytochrome P450s: characterization of the orphans;Guengerich;Biochem. Biophys. Res. Commun.,2005

2. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol. Therapeut.,2013

3. Cytochrome P450 systems—biological variations of electron transport chains;Hannemann;Biochim. Biophys. Acta Gen. Subj.,2007

4. Identification by site-directed mutagenesis of two lysine residues in cholesterol side chain cleavage cytochrome P450 that are essential for adrenodoxin binding;Wada;J. Biol. Chem.,1992

5. NADPH P450 oxidoreductase: structure, function, and pathology of diseases;Pandey;Pharmacol. Therapeut.,2013

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