Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9-Reference-Cited by-同舟云学术

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Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9

Published:2021-01 Issue: Volume:180 Page:23-29
ISSN:0300-9084
Container-title:Biochimie
language:en
Short-container-title:Biochimie

Author:

Noori Ali-Reza,Tashakor Amin,Nikkhah Maryam,Eriksson Leif A.,Hosseinkhani Saman,Fearnhead Howard O.

Funder

EPIC

National University of Ireland Galway

Swedish research council

Tarbiat Modares University

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference34 articles.

1. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3;Zou;Cell,1997

2. The Apaf-1 apoptosome: a large caspase-activating complex;Cain;Biochimie,2002

3. Regulation of the apaf-1-caspase-9 apoptosome;Bratton;J. Cell Sci.,2010

4. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade;Li;Cell,1997

5. Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1;Zhou;Genes Dev.,2015

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