Crystal structure of Escherichia coli thymidylate synthase with FdUMP and 10-propargyl-5,8-dideazafolate
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Genetics,Molecular Biology,Molecular Medicine
Reference22 articles.
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4. Atomic structure of thymidylate synthase: Target for rational drug design;Hardy;Science,1987
5. Stacked beta-bulges in thymidylate synthase account for a novel right-handed rotation between opposing beta sheets;Matthews;J. Mol. Biol.,1989
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3. Differences in natural ligand and fluoropyrimidine binding to human thymidylate synthase identified by transient-state spectroscopic and continuous variation methods;Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology;2002-05
4. Crystal Structures of a Unique Thermal-Stable Thymidylate Synthase from Bacillus subtilis,;Biochemistry;1998-09-26
5. The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 å resolution: implications for a new mode of inhibition;Structure;1996-01
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