Role of glutathione in cellular resistance to alkylating agents

Author:

Colvin O.Michael,Friedman Henry S.,Gamcsik Michael P.,Fenselau Catherine,Hilton John

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology,Molecular Medicine

Reference20 articles.

1. Tumor sulfhydryl levels and sensitivity to the nitrogen mustard merophan;Calcutt;Biochem. Pharmacol.,1963

2. Reduction in glutathione content of L-PAM resistant L1210 cell confers drug sensitivity;Suzukaka;Biochem. Pharmacol.,1982

3. Cyclophosphamide resistance in medulloblastoma;Friedman;Cancer Res.,1992

4. Characterization of melphalan-glutathione adducts whose formation is catalysed by glutathione S-transferases;Dulik;Biochem. Pharmacol.,1986

5. Conversion of melphalan to 4-(glutathionyl)phenylalanine.A novel mechanism for conjugation by glutathione-S-transferases;Dulik;Drug Metab. Dispos.,1987

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