The basis for intrinsic drug resistance or sensitivity to methotrexate

Author:

Bertino J.R.,Lin J.,Pizzorno G.,Wei Wei Li ,Chang Y.M.

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology,Molecular Medicine

Reference10 articles.

1. Nitrogen mustard therapy: use of methylbis (β-chorethyl) amino hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders;Goodman;J. Am. Med. Assoc.,1946

2. Temporary remissions in acute leukemia in children produced by folic antagonist 4-amethopterodylglutamic acid (aminopterin);Farber;New Engl. J. Med.,1948

3. Drug resistance: new approaches to treatment;Bertino,1986

4. Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro;Yalowich;Biochem. Pharmacol.,1985

5. Development of an assay system for the detection and classification of methotrexate resistance in fresh human leukemic cells;Rodenhuis;Cancer Res.,1986

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