SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress-Reference-Cited by-同舟云学术

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SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress

Published:2013-03 Issue: Volume:743-744 Page:26-32
ISSN:0027-5107
Container-title:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
language:en
Short-container-title:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Author:

Nagaria Pratik,Svilar David,Brown Ashley R.,Wang Xiao-hong,Sobol Robert W.,Wyatt Michael D.

Funder

NIH/NCRR

NIH/NCI

National Institutes of Health

University of Pittsburgh Department of Pharmacology and Chemical Biology

Cancer Center Support Grant from the National Institutes of Health

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics,Molecular Biology

Reference33 articles.

1. Uracil in DNA: consequences for carcinogenesis and chemotherapy;Berger;Biochem. Pharmacol.,2008

2. Participation of DNA repair in the response to 5-fluorouracil;Wyatt;Cell. Mol. Life Sci.,2009

3. Uracil in DNA—occurrence, consequences and repair;Krokan;Oncogene,2002

4. 5-Fluorouracil incorporated into DNA is excised by the smug1 DNA glycosylase to reduce drug cytotoxicity;An;Cancer Res.,2007

5. Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts;Andersen;Carcinogenesis,2005

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Biomarkers for chemotherapy and drug resistance in the mismatch repair pathway;Clinica Chimica Acta;2023-04

2. A regulatory network comprising let-7 miRNA and SMUG1 is associated with good prognosis in ER+ breast tumours;Nucleic Acids Research;2022-09-26

3. 5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition;Biomedicine & Pharmacotherapy;2021-05

4. Inhibitors of DNA Glycosylases as Prospective Drugs;International Journal of Molecular Sciences;2020-04-28

5. Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer Patients;International Journal of Molecular Sciences;2020-04-02

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