Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice
Author:
Publisher
Elsevier BV
Subject
Behavioral Neuroscience,Endocrine and Autonomic Systems,Immunology
Reference25 articles.
1. IFN-gamma Production by amyloid beta-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease;Browne;J. Immunol.,2013
2. Arginase 1+ microglia reduce Abeta plaque deposition during IL-1beta-dependent neuroinflammation;Cherry;J Neuroinflammation,2015
3. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases;Coll;Nat. Med.,2015
4. Alpha-TLR2 antibody attenuates the Abeta-mediated inflammatory response in microglia through enhanced expression of SIGIRR;Costello;Brain Behav. Immun.,2015
5. The age-related neuroinflammatory environment promotes macrophage activation, which negatively impacts synaptic function;Costello;Neurobiol. Aging,2016
Cited by 402 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Notopterygium incisum roots extract (NRE) alleviates neuroinflammation pathology in Alzheimer’s disease through TLR4-NF-κB pathway;Journal of Ethnopharmacology;2024-12
2. The PGC-1α/ERRα/ULK1 pathway contributes to Perioperative neurocognitive disorders by inducing mitochondrial dysfunction and activating NLRP3 inflammasome in aged mice;Neuropharmacology;2024-12
3. Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammatory responses;Mitochondrion;2024-11
4. Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer’s disease;Neuroscience & Biobehavioral Reviews;2024-10
5. Modulating NLRP3 splicing with antisense oligonucleotides to control pathological inflammation;2024-09-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3