CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology

Author:

Tecle H.,Schwarz R.D.,Barrett S.D.,Callahan M.J.,Caprathe B.W.,Davis R.E.,Doyle P.,Emmerling M.,Lauffer D.J.,Mirzadegan T.,Moreland D.W.,Lipiniski W.,Nelson C.,Raby C.,Spencer C.,Spiegel K.,Thomas A.J.,Jaen J.C.

Publisher

Elsevier

Reference29 articles.

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2. Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells;Bolden;J. Pharmacol. Exp. Ther.,1992

3. Identification of a family of muscarinic acetylcholine receptor genes;Bonner;Science,1987

4. Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors;Braeuner-Osborne;J. Med. Chem.,1995

5. Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells;Braeuner-Osborne;Eur. J. Pharmacol.,1996

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