FDA-drug screening identifies deptropine inhibiting hepatitis E virus involving the NF-κB-RIPK1-caspase axis

Author:

Qu Changbo,Li Yang,Li Yunlong,Yu Peifa,Li Pengfei,Donkers Joanne M.,van de Graaf Stan F.J.,de Man Robert A.,Peppelenbosch Maikel P.,Pan Qiuwei

Funder

Dutch Digestive Foundation

MLDS

Dutch Cancer Society

VIDI

Netherlands Organisation for Scientific Research

China Scholarship Council

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference51 articles.

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2. Viral modulation of cell death by inhibition of caspases;Cassens;Arch. Immunol. Ther. Exp.,2003

3. Inhibition of Ebola and marburg virus entry by G protein-coupled receptor antagonists;Cheng;J. Virol.,2015

4. Viral hijacking of host caspases: an emerging category of pathogen-host interactions;Connolly;Cell Death Differ.,2017

5. Hepatitis E virus in patients with acute severe liver injury;Crossan;World J. Hepatol.,2014

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