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Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease

  • Published:2020-03 Issue: Volume:175 Page:104707
  • ISSN:0166-3542
  • Container-title:Antiviral Research
  • language:en
  • Short-container-title:Antiviral Research

Author:

Quek Jun Ping,Liu Shuang,Zhang Zhenzhen,Li Yan,Ng Elizabeth Yihui,Loh Ying Ru,Hung Alvin W.,Luo Dahai,Kang CongBao

Funder

Singapore National Research Foundation

Singapore National Medical Research Council

Singapore Ministry of Health’s National Medical Research Council

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference49 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. Sect. D Biol. Crystallogr.,2010

2. Towards automated crystallographic structure refinement with phenix.refine;Afonine;Acta crystallographica. Section D, Biological crystallography,2012

3. iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM;Battye;Acta Crystallogr. Sect. D Biol. Crystallogr.,2011

4. Zika virus as a cause of neurologic disorders;Broutet;N. Engl. J. Med.,2016

5. Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease;Chen;Cell Res.,2016
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