Strong and multi-antigen specific immunity by hepatitis B core antigen (HBcAg)-based vaccines in a murine model of chronic hepatitis B: HBcAg is a candidate for a therapeutic vaccine against hepatitis B virus

Author:

Akbar Sheikh Mohammad Fazle,Chen Shiyi,Al-Mahtab Mamun,Abe Masanori,Hiasa Yoichi,Onji Morikazu

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference29 articles.

1. Development of a nasal vaccine for chronic hepatitis B infection that uses the ability of hepatitis B core antigen to stimulate a strong Th1 response against hepatitis B surface antigen;Aguilar;Immunol. Cell. Biol.,2004

2. Safety and immunogenecity of hepatitis B surface antigen-pulsed dendritic cells in patients with chronic hepatitis B;Akbar;J. Viral. Hepat.,2010

3. Immune modulator and antiviral potential of dendritic cells pulsed with both hepatitis B surface antigen and core antigen for treating chronic HBV infection;Akbar;Antivir. Ther.,2010

4. Therapeutic potential of a novel therapeutic vaccine containing both hepatitis B surface antigen (HBsAg) and hepatitis B core antigen (HBcAg) administered through mucosal and parental route in patients with chronic hepatitis B;Akbar;Hepatology,2010

5. Expression and replication of hepatitis B virus genome in transgenic mice;Araki;Proc. Natl. Acad. Sci. USA,1989

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