Telaprevir-S isomer enhances ribavirin exposure and the ribavirin-related haemolytic anaemia in a concentration-dependent manner
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Published:2014-09
Issue:
Volume:109
Page:7-14
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ISSN:0166-3542
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Container-title:Antiviral Research
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language:en
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Short-container-title:Antiviral Research
Author:
De Nicolò Amedeo, Boglione Lucio, Ciancio Alessia, Cusato Jessica, Strona Silvia, Cardellino Chiara SimonaORCID, Mohamed Abdi Adnan, Cariti Giuseppe, Troshina Giulia, Caviglia Gian Paolo, Smedile Antonina, Rizzetto Mario, Di Perri Giovanni, D’Avolio AntonioORCID
Subject
Virology,Pharmacology
Reference34 articles.
1. Asselah, T., Pasmant, E., Lyoumi, S., 2010. Unraveling the genetic predisposition of ribavirin-induced anaemia. J Hepatol. 2. Significant early higher ribavirin plasma concentrations in patients receiving a triple therapy with pegylated interferon, ribavirin and telaprevir;Boglione;J. Viral. Hepat.,2014 3. F-33 Early ribavirin plasma concentration and ITPA polymorphisms as determinants of anemia after one month of anti-HCV therapy;Caviglia;Digest. Liver Dis.,2012 4. A small percentage of patients with hepatitis C receive triple therapy with boceprevir or telaprevir;Chen;Clin. Gastroenterol. Hepatol.,2013 5. Ribavirin pharmacokinetics and interleukin 28B plus cytochrome P450 27B1 single-nucleotide polymorphisms as predictors of response to pegylated interferon/ribavirin treatment in patients infected with hepatitis C virus genotype 1/4;D’Avolio;Hepatology,2011
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