First clinical description of letermovir resistance mutation in cytomegalovirus UL51 gene and potential impact on the terminase complex structure

Author:

Muller ClotildeORCID,Tilloy Valentin,Frobert Emilie,Feghoul Linda,Garrigue Isabelle,Lepiller Quentin,Mirand Audrey,Sidorov Egor,Hantz Sébastien,Alain SophieORCID

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference29 articles.

1. Letermovir breakthroughs during the French Named Patient Programme: interest of monitoring blood concentration in clinical practice;Alain;J. Antimicrob. Chemother.,2020

2. Contrasting effect of new HCMV pUL54 mutations on antiviral drug susceptibility: benefits and limits of 3D analysis;Andouard;Antivir. Res.,2016

3. Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: a new approach for construction of HCMV mutants;Borst;J. Virol.,1999

4. The human cytomegalovirus UL51 protein is essential for viral genome cleavage-packaging and interacts with the terminase subunits pUL56 and pUL89;Borst;J. Virol.,2013

5. Original article Putative functional domains of human cytomegalovirus pUL56 involved in dimerization and benzimidazole D-ribonucleoside activity;Champier;Antivir. Ther.,2008

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