A virus-like particle candidate vaccine based on CRISPR/Cas9 gene editing technology elicits broad-spectrum protection against SARS-CoV-2

Author:

Wang Weiqi,Wang Shen,Meng Xianyong,Zhao Yongkun,Li Nan,Wang Tiecheng,Feng Na,Yan Feihu,Xia Xianzhu

Funder

Chinese Academy of Agricultural Sciences

Publisher

Elsevier BV

Reference57 articles.

1. SARS-CoV-2 Omicron BA.5: Evolving Tropism and Evasion of Potent Humoral Responses and Resistance to Clinical Immunotherapeutics Relative to Viral Variants of Concern;Aggarwal,2022

2. Systems vaccinology of the BNT162b2 mRNA vaccine in humans;Arunachalam;Nature,2021

3. Covid-19 breakthrough infections in vaccinated health care workers;Bergwerk;N. Engl. J. Med.,2021

4. Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials;Bikard;Nat. Biotechnol.,2014

5. Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine;Blanchard;J. Gen. Virol.,1998

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Virus-like particles in poultry disease: an approach to effective and safe vaccination;Frontiers in Veterinary Science;2024-09-09

2. CRISPR-Cas based genome editing for eradication of human viruses;Progress in Molecular Biology and Translational Science;2024

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