The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness-Reference-Cited by-同舟云学术

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness

Published:2017-01 Issue: Volume:137 Page:6-13
ISSN:0166-3542
Container-title:Antiviral Research
language:en
Short-container-title:Antiviral Research

Author:

Tu Véronique^ORCID,Abed Yacine,Barbeau Xavier,Carbonneau Julie,Fage Clément,Lagüe Patrick,Boivin Guy

Funder

Canadian Institutes of Health Research

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference43 articles.

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3. Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets;Abed;J. Virol.,2014

4. Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses;Baz;J. Infect. Dis.,2010

5. Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone phi, psi and side-chain chi(1) and chi(2) dihedral angles;Best;J. Chem. Theory Comput.,2012

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