Partial selective inhibition of HIV-1 reverse transcriptase and human DNA polymerases γ and β by thiated 3′-fluorothymidine analogue 5′-triphosphates

Author:

Wińska Patrycja,Miazga Agnieszka,Poznański Jarosław,Kulikowski Tadeusz

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference41 articles.

1. Anti-retrovirus activity of 3′-fluoro- and 3′-azido-substituted pyrimidine 2′,3′-dideoxynucleoside analogues;Balzarini;Biochem. Pharmacol.,1988

2. Halogeno-3′-fluoro-2′,3′-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3′-fluoro-2′,3′-dideoxy-5-chlorouridine;Balzarini;Mol. Pharmacol.,1989

3. Significant levels of intracellular stavudine triphosphate are found in HIV-infected zidovudine-treated patients;Becher;AIDS,2003

4. Molecular insights into NRTI inhibition and mitochondrial toxicity revealed from a structural model of the human mitochondrial DNA polymerase;Bienstock;Mitochondrion,2004

5. Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs;Cheng;J. Biol. Chem.,1987

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