Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

Author:

Habib Abdella M.,Okorokov Andrei L.,Hill Matthew N.,Bras Jose T.,Lee Man-Cheung,Li Shengnan,Gossage Samuel J.,van Drimmelen Marie,Morena Maria,Houlden Henry,Ramirez Juan D.,Bennett David L.H.,Srivastava Devjit,Cox James J.

Funder

Cumming School of Medicine, University of Calgary

Medical Research Council

Wellcome Trust

Alzheimer's Society

University of Cambridge

National Institutes of Health

Harvard University

Canadian Institutes of Health Research

CIHR

Publisher

Elsevier BV

Subject

Anesthesiology and Pain Medicine

Reference27 articles.

1. Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist;Deutsch;Biochem Pharmacol,1993

2. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides;Cravatt;Nature,1996

3. The role of the endocannabinoid system in pain;Woodhams;Handb Exp Pharmacol,2015

4. The endocannabinoid system and the brain;Mechoulam;Annu Rev Psychol,2013

5. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase;Cravatt;Proc Natl Acad Sci USA,2001

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