Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid-Reference-Cited by-同舟云学术

Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid

Published:2023-02 Issue:2 Volume:130 Page:154-164
ISSN:0007-0912
Container-title:British Journal of Anaesthesia
language:en
Short-container-title:British Journal of Anaesthesia

Author:

Manzella Francesca M.,Cabrera Omar H.,Wilkey Davis,Fine-Raquet Brier,Klawitter Jelena,Krishnan Kathiresan,Covey Douglas F.,Jevtovic-Todorovic Vesna,Todorovic Slobodan M.

Funder

NIGMS

Publisher

Elsevier BV

Subject

Anesthesiology and Pain Medicine

Reference31 articles.

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3. Sex differences in pharmacokinetics and pharmacodynamics;Soldin;Annu Rev Pharmacol Toxicol,2009

4. The T-type calcium channel isoform Cav 3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile;Timic Stamenic;Br J Anaesth,2021

5. Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca v3.3 channels;Joksovic;Br J Pharmacol,2005

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