The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1

Author:

Duffin Rodger,Leitch Andrew E.,Sheldrake Tara A.,Hallett John M.,Meyer Colette,Fox Sarah,Alessandri Ana L.,Martin Morag C.,Brady Hugh J.,Teixeira Mauro M.,Dransfield Ian,Haslett Christopher,Rossi Adriano G.

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference50 articles.

1. The eosinophil;Rothenberg;Annu. Rev. Immunol.,2006

2. Pharmacology of the eosinophil;Giembycz;Pharmacol. Rev.,1999

3. Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa;Leitch;Mucosal. Immunol.,2008

4. Reduced eosinophil apoptosis in induced sputum correlates with asthma severity;Duncan;Eur. Respir. J.,2003

5. Delayed eosinophil apoptosis in asthma;Kankaanranta;J. Allergy Clin. Immunol.,2000

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