Truncated KCNQ1 mutant, A178fs/105, forms hetero-multimer channel with wild-type causing a dominant-negative suppression due to trafficking defect-Reference-Cited by-同舟云学术

Truncated KCNQ1 mutant, A178fs/105, forms hetero-multimer channel with wild-type causing a dominant-negative suppression due to trafficking defect

Published:2004-08-21 Issue:1-3 Volume:574 Page:145-150
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:

Author:

Aizawa Yoshiyasu,Ueda Kazuo,Wu Long-mei,Inagaki Natsuko,Hayashi Takeharu,Takahashi Megumi,Ohta Masaaki,Kawano Seiko,Hirano Yuji,Yasunami Michio,Aizawa Yoshifusa,Kimura Akinori,Hiraoka Masayasu

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference16 articles.

1. Long QT syndrome: novel insights into the mechanisms of cardiac arrhythmias

2. Genomic Organization of the KCNQ1 K + Channel Gene and Identification of C-Terminal Mutations in the Long-QT Syndrome

3. Site-directed mutagenesis by overlap extension using the polymerase chain reaction

4. Effects of Na+ Channel Blocker, Pilsicainide, on HERG Current Expressed in HEK-293 Cells

5. Novel mutations in KvLQT1 that affect Iks activation through interactions with Isk

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1. Disruption of a Conservative Motif in the C-Terminal Loop of the KCNQ1 Channel Causes LQT Syndrome;International Journal of Molecular Sciences;2022-07-19

2. Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region;European Heart Journal;2021-09-10

3. Expanding the genetic and phenotypic relevance of KCNB1 variants in developmental and epileptic encephalopathies: 27 new patients and overview of the literature;Human Mutation;2019-10-04

4. Molecular pathogenesis of long QT syndrome type 1;Journal of Arrhythmia;2016-10

5. A novel frameshift mutation in KCNQ4 in a family with autosomal recessive non-syndromic hearing loss;Biochemical and Biophysical Research Communications;2015-08