A computational tool to predict the evolutionarily conserved protein-protein interaction hot-spot residues from the structure of the unbound protein
Author:
Funder
National Center for Supercomputing Applications
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.febslet.2013.11.004/fullpdf
Reference43 articles.
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2. Hot-spot mimicry of a cytokine receptor by a small molecule;Thanos;Proc. Natl. Acad. Sci. USA,2006
3. Assessing helical protein interfaces for inhibitor design;Bullock;J. Am. Chem. Soc.,2011
4. High-resolution epitope mapping of high-receptor interactions by alanine-scanning mutagenesis;Cunningham;Science,1989
5. Protein-protein interaction hotspots carved into sequences;Ofran;PLoS Comput. Biol.,2007
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