An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria-Reference-Cited by-同舟云学术

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An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria

Published:2015-05-14 Issue:15 Volume:589 Page:1855-1862
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:

Author:

Hughes Linda,Carton Robert,Minguzzi Stefano,McEntee Gráinne,Deinum Eva E.,O'Connell Mary J.,Parle-McDermott Anne

Funder

Health Research Board

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.febslet.2015.05.017/fullpdf

Reference29 articles.

1. Cancer research: from folate antagonism to molecular targets;Bertino;Best Pract. Res. Clin. Haematol.,2009

2. Gene amplification, drug resistance, and cancer;Schimke;Cancer Res.,1984

3. Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target;Yuthavong;Proc. Natl. Acad. Sci. USA,2012

4. The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional;McEntee;Proc. Natl. Acad. Sci. USA,2011

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1. SGLT2 inhibition leads to a restoration of hepatic and circulating metabolites involved in the folate cycle and pyrimidine biosynthesis;American Journal of Physiology-Gastrointestinal and Liver Physiology;2024-08-01

2. The Differential Translation Capabilities of the Human DHFR2 Gene Indicates a Developmental and Tissue-Specific Endogenous Protein of Low Abundance;Molecular & Cellular Proteomics;2024-03

3. Pairing structural reconstruction with catalytic competence to evaluate the mechanisms of key enzymes in the folate‐mediated one‐carbon pathway;The FEBS Journal;2022-03-31

4. Mitochondrial NAD(P)+ Transhydrogenase: From Molecular Features to Physiology and Disease;Antioxidants & Redox Signaling;2021-08-05

5. Mitochondrial NAD(P)+ Transhydrogenase is Unevenly Distributed in Different Brain Regions, and its Loss Causes Depressive-like Behavior and Motor Dysfunction in Mice;Neuroscience;2020-08

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