A new facile one-pot preparation of pentafluorophenyl (Pfp) and 3,4-dihydro-4-oxo-1,2,3-benzotriazine-3-yl (Dhbt) esters of Fmoc amino acids.
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference13 articles.
1. Racemisierung bei Peptidsynthesen
2. Eine neue Methode zur Synthese von Peptiden: Aktivierung der Carboxylgruppe mit Dicyclohexylcarbodiimid und 3‐Hydroxy‐4‐oxo‐3.4‐dihydro‐l.2.3‐benzotriazin
3. Peptide synthesis. Part 12. 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl esters of fluorenylmethoxycarbonyl amino acids as self-indicating reagents for solid phase peptide synthesis
4. Peptide synthesis. Part 13. Feedback control in solid phase synthesis. Use of fluorenylmethoxycarbonyl amino acid 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl esters in a fully automated system
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1. Active ester-based peptide bond formation and its application in peptide synthesis;Organic Chemistry Frontiers;2023
2. 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Toluene-4-sulfonate (DMT/NMM/TsO− ) Universal Coupling Reagent for Synthesis in Solution;Helvetica Chimica Acta;2017-12-21
3. Amino acid chlorides: a journey from instability and racemization toward broader utility in organic synthesis including peptides and their mimetics;Tetrahedron;2015-05
4. Methods for the Peptide Synthesis and Analysis;Peptide Chemistry and Drug Design;2015-02-13
5. 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one;Encyclopedia of Reagents for Organic Synthesis;2014-05-27
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