A facile synthesis of functionally complex isoxazole derivatives
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference12 articles.
1. Isoxazole Chemistry Since 1963
2. Generation and reactions of the dianion of 3-hydroxy-5-methylisoxazole, a convenient .beta.-oxo amide synthon. Total synthesis of muscimol
3. Directed metalation of tertiary benzamides. Silicon protection of ortho sites and ortho methyl groups
4. Ortho metalation directed by .alpha.-amino alkoxides
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2. 4-isoxazolyl-1,4-dihydropyridines: a tale of two scaffolds;Future Medicinal Chemistry;2014-05
3. 3-(1,3-Diphenylpropan-2-yl)-4-methyl-6-phenylisoxazolo[3,4-d]pyridazin-7(6H)-one;Acta Crystallographica Section E Structure Reports Online;2013-10-23
4. 4-Isoxazolyl-1,4-dihydropyridines exhibit binding at the multidrug-resistance transporter;Bioorganic & Medicinal Chemistry;2012-11
5. Synthetic utility of epoxides for chiral functionalization of isoxazoles;Tetrahedron Letters;2008-05
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