Enantioselective synthesis of the (syn,anti)-1-amino-2,3-diol subunit of renin inhibitors by reaction of β-Lactams with a Grignard reagent
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference14 articles.
1. A convenient stereoselective synthesis of 1,2,3-aminodiols from .alpha.-amino acids
2. A versatile, efficient synthesis of (−)-(2S, 3R, 4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, the abbott pseudodipeptidyl insert
3. A Practical Synthesis of the Dihydroxyethylene Dipeptide Isostere, (2S, 3R, 4S) 2-[(tert-Butyloxycarbonyl)amino]-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, from D-Isoascorbic Acid
4. A versatile and stereospecific synthesis of a dihydroxyethylene Dipeptide Isostere of Renin inhibitors from D-ribose
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