FR66979 requires reductive activation to cross-link DNA efficiently
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference8 articles.
1. DNA cross-linking studies on FR900482 : observations on the mode of activation
2. DNA interstrand cross-linking by reductively activated FR900482 and FR66979
3. Determination of DNA cross-linking sequence specificity of FR66979: Observations on the mode of action of the FR900482 class of anti-tumor compounds
4. Covalent Structure of the DNA-DNA Interstrand Cross-Link Formed by Reductively Activated FR66979 in Synthetic DNA Duplexes
5. Synthetic approaches toward FR-900482. I. Stereoselective synthesis of a pentacyclic model compound
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