A total synthesis of (±)-Mitomycin K. Oxidation of the mitosene C9-9a double bond by (hexamethylphosphoramido)oxodiperoxomolybdenum (VI) (MoO5

A total synthesis of (±)-Mitomycin K. Oxidation of the mitosene C9-9a double bond by (hexamethylphosphoramido)oxodiperoxomolybdenum (VI) (MoO5 · HMPA)

Published:1996-08 Issue:34 Volume:37 Page:6049-6052
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Wang Zheng,Jimenez Leslie S

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference25 articles.

1. Isolation and Structure of a Covalent Cross-Link Adduct Between Mitomycin C and DNA

2. DNA cross-linking by intermediates in the mitomycin activation cascade

3. Mitomycins and Porfiromycin: Chemical Mechanism of Activation and Cross-linking of DNA

4. Recognition of mitomycin C-DNA monoadducts by UVRABC nuclease

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