Activation State-Dependent Binding of Small Molecule Kinase Inhibitors: Structural Insights from Biochemistry-Reference-Cited by-同舟云学术

Activation State-Dependent Binding of Small Molecule Kinase Inhibitors: Structural Insights from Biochemistry

Published:2010-11 Issue:11 Volume:17 Page:1241-1249
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Wodicka Lisa M.,Ciceri Pietro,Davis Mindy I.,Hunt Jeremy P.,Floyd Mark,Salerno Sara,Hua Xuequn H.,Ford Julia M.,Armstrong Robert C.,Zarrinkar Patrick P.,Treiber Daniel K.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference37 articles.

1. Targeting the unactivated conformations of protein kinases for small molecule drug discovery;Alton;Expert Opin. Drug Discov.,2008

2. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase;Atwell;J. Biol. Chem.,2004

3. Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases;Carter;Proc. Natl. Acad. Sci. USA,2005

4. Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance;DiNitto;J. Biochem.,2010

5. KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients;Gajiwala;Proc. Natl. Acad. Sci. USA,2009

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