Ancestral Tryptophan Synthase Reveals Functional Sophistication of Primordial Enzyme Complexes

Author:

Busch Florian,Rajendran Chitra,Heyn Kristina,Schlee Sandra,Merkl Rainer,Sterner Reinhard

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

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3. Serine modulates substrate channeling in tryptophan synthase. A novel intersubunit triggering mechanism;Anderson;J. Biol. Chem.,1991

4. Assessing the prediction fidelity of ancestral reconstruction by a library approach;Bar-Rogovsky;Protein Eng. Des. Sel.,2015

5. A genomic timescale of prokaryote evolution: insights into the origin of methanogenesis, phototrophy, and the colonization of land;Battistuzzi;BMC Evol. Biol.,2004

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