Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11

Author:

Dickson Paige,Simanski ScottORCID,Ngundu John Maina,Kodadek Thomas

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

1. Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development;Al-Shami;PLoS One,2010

2. A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer;Anchoori;Cancer Cell,2013

3. Knockdown of the novel proteasome subunit Adrm1 located on the 20q13 amplicon inhibits colorectal cancer migration, survivability and tumorigenicity;Chen;Oncol. Rep.,2009

4. Inhibition of proteasome deubiquitinating activity as a new cancer therapy;D'Arcy;Nat. Med.,2011

5. Deubiquitinase inhibition as a cancer therapeutic strategy;D'Arcy;Pharmacol. Ther.,2015

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