Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A-Reference-Cited by-同舟云学术

Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A

Published:2021-06 Issue:6 Volume:28 Page:825-834.e6
ISSN:2451-9456
Container-title:Cell Chemical Biology
language:en
Short-container-title:Cell Chemical Biology

Author:

Naineni Sai Kiran,Liang Jason^ORCID,Hull Kenneth^ORCID,Cencic Regina^ORCID,Zhu Mingzhao,Northcote Peter,Teesdale-Spittle Paul,Romo Daniel,Nagar Bhushan,Pelletier Jerry

Funder

Natural Sciences and Engineering Research Council of Canada

National Research Council Canada

Canadian Institutes of Health Research

Province of Saskatchewan

Western Economic Diversification Canada

University of Saskatchewan

National Institutes of Health

National Institute of General Medical Sciences

Baylor University-CPRIT Drug Lead Discovery Laboratory

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

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3. Targeting the translation machinery in cancer;Bhat;Nat. Rev. Drug Discov.,2015

4. RNA-mediated sequestration of the RNA helicase eIF4A by pateamine A inhibits translation initiation;Bordeleau;Chem. Biol.,2006

5. Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation;Bordeleau;Proc. Natl. Acad. Sci. U S A,2005

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