New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation

Author:

Arwood Matthew L.,Liu Yao,Harkins Shannon K.,Weinstock David M.,Yang Lei,Stevenson Kristen E.,Plana Olivia D.,Dong Jingyun,Cirka Haley,Jones Kristen L.,Virtanen Anniina T.,Gupta Dikshat G.,Ceas Amanda,Lawney Brian,Yoda Akinori,Leahy Catharine,Hao Mingfeng,He Zhixiang,Choi Hwan Geun,Wang Yaning,Silvennoinen Olli,Hubbard Stevan R.,Zhang Tinghu,Gray Nathanael S.ORCID,Li Loretta S.ORCID

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference52 articles.

1. JAK-mutant myeloproliferative neoplasms;Levine;Curr. Top. Microbiol. Immunol.,2012

2. Mutant calreticulin requires both its mutant C-terminus and the thrombopoietin receptor for oncogenic transformation;Elf;Cancer Discov.,2016

3. Targetable kinase-activating lesions in ph-like acute lymphoblastic leukemia;Roberts;N. Engl. J. Med.,2014

4. Has ph-like ALL superseded Ph+ ALL as the least favorable subtype?;Tran;Best Pract. Res. Clin. Haematol.,2021

5. Cooperative epigenetic modulation by cancer amplicon genes;Rui;Cancer Cell,2010

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