HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter-Reference-Cited by-同舟云学术

HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter

Published:2012-07 Issue:7 Volume:19 Page:806-818
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Kiselyuk Alice,Lee Seung-Hee,Farber-Katz Suzette,Zhang Mingjun,Athavankar Sonalee,Cohen Tom,Pinkerton Anthony B.,Ye Mao,Bushway Paul,Richardson Adam D.,Hostetler Heather A.,Rodriguez-Lee Mariam,Huang Li,Spangler Benjamin,Smith Layton,Higginbotham Jennifer,Cashman John,Freeze Hudson,Itkin-Ansari Pamela,Dawson Marcia I.,Schroeder Friedhelm,Cang Yong,Mercola Mark,Levine Fred

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference51 articles.

1. Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain;Adler;Cell,1988

2. An enhancer element 6 kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors;Bailly;Nucleic Acids Res.,2001

3. Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4 alpha;Bartoov-Shifman;J. Biol. Chem.,2002

4. Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha;Bogan;J. Mol. Biol.,2000

5. Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays;Bolotin;Hepatology,2010

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