KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes

Author:

Duan Lingling,Rai Ganesha,Roggero Carlos,Zhang Qing-Jun,Wei Qun,Ma Shi Hong,Zhou Yunyun,Santoyo John,Martinez Elisabeth D.,Xiao Guanghua,Raj Ganesh V.,Jadhav Ajit,Simeonov Anton,Maloney David J.,Rizo Josep,Hsieh Jer-Tsong,Liu Zhi-Ping

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference40 articles.

1. KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells;Berry;Cancer Res.,2013

2. Histone lysine methylation dynamics: establishment, regulation, and biological impact;Black;Mol. Cell,2012

3. Identification and functional characterization of the human and murine polo-like kinase (Plk) promoter;Bräuninger;Oncogene,1995

4. ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer;Cai;J. Clin. Invest.,2013

5. Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors;Centenera;Clin. Cancer Res.,2012

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