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Ligand-directed bias of G protein signaling at the dopamine D2 receptor

  • Published:2021-07 Issue: Volume: Page:
  • ISSN:2451-9456
  • Container-title:Cell Chemical Biology
  • language:en
  • Short-container-title:Cell Chemical Biology

Author:

Von Moo EeORCID,Harpsøe Kasper,Hauser Alexander S.ORCID,Masuho Ikuo,Bräuner-Osborne Hans,Gloriam David E.,Martemyanov Kirill A.ORCID

Funder

National Institutes of Health

National Institute of Mental Health

National Institute on Drug Abuse

Carlsberg Foundation

Lundbeck Foundation

Novo Nordisk Fonden

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference93 articles.

1. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors;Alexander;Br. J. Pharmacol.,2019

2. Discovery of beta-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy;Allen;Proc. Natl. Acad. Sci. U S A,2011

3. GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells;Anderson;Proc. Natl. Acad. Sci. U S A,2020

4. Further association study on dopamine D2 receptor variant S311C in schizophrenia and affective disorders;Arinami;Am. J. Med. Genet.,1996

5. Dopamine receptors - IUPHAR review 13;Beaulieu;Br. J. Pharmacol.,2015

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1. Progress on the development of Class A GPCR‐biased ligands;British Journal of Pharmacology;2024-09-11

2. G protein-coupled receptor (GPCR) pharmacogenomics;Critical Reviews in Clinical Laboratory Sciences;2024-08-09

3. Natural Product-Inspired Dopamine Receptor Ligands;Journal of Medicinal Chemistry;2024-07-22

4. Biased signalling in analgesic research and development;Current Opinion in Pharmacology;2024-06

5. Regulatory roles of dopamine D2 receptor in milk protein production and apoptosis in mammary epithelial cells;Experimental Cell Research;2024-06
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