Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds-Reference-Cited by-同舟云学术

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Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds

Published:2021-12 Issue: Volume: Page:
ISSN:2451-9456
Container-title:Cell Chemical Biology
language:en
Short-container-title:Cell Chemical Biology

Author:

Akbarzadeh Mohammad,Deipenwisch Ilka,Schoelermann Beate,Pahl Axel,Sievers Sonja^ORCID,Ziegler Slava,Waldmann Herbert

Funder

Max-Planck-Gesellschaft

European Regional Development Fund

European Commission

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference62 articles.

1. WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop;Agajanian;Cell Rep.,2019

2. Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy;Arnst;Med. Res. Rev.,2019

3. The polypharmacology browser: a web-based multi-fingerprint target prediction tool using ChEMBL bioactivity data;Awale;J. Cheminform.,2017

4. Web-based tools for polypharmacology prediction;Awale;Methods Mol. Biol.,2019

5. Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts;Belmont;Cell,1990

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1. Distinct profile of antiviral drugs effects in aortic and pulmonary endothelial cells revealed by high-content microscopy and cell painting assays;Toxicology and Applied Pharmacology;2024-09

2. Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines;2024-08-27

3. Unleashing the potential of cell painting assays for compound activities and hazards prediction;Frontiers in Toxicology;2024-07-17

4. Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay;Journal of Medicinal Chemistry;2024-07-17

5. Polypharmacology prediction: the long road toward comprehensively anticipating small-molecule selectivity to de-risk drug discovery;Expert Opinion on Drug Discovery;2024-07-14

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