Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference70 articles.
1. The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib;Albers;Leukemia,2013
2. FLT3 inhibitors in acute myeloid leukemia: ten frequently asked questions;Antar;Leukemia,2020
3. FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L);Bagrintseva;Blood,2005
4. Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases;Baska;Eur. J. Med. Chem.,2019
5. How to distinguish between the activity of HDAC1-3 and HDAC6 with western blot;Beyer;Methods Mol. Biol.,2017
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