Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction-Reference-Cited by-同舟云学术

Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction

Published:2019-03 Issue:3 Volume:26 Page:378-389.e13
ISSN:2451-9456
Container-title:Cell Chemical Biology
language:en
Short-container-title:Cell Chemical Biology

Author:

Bum-Erdene Khuchtumur,Zhou Donghui,Gonzalez-Gutierrez Giovanni,Ghozayel Mona K.,Si Yubing,Xu David,Shannon Harlan E.,Bailey Barbara J.,Corson Timothy W.,Pollok Karen E.,Wells Clark D.,Meroueh Samy O.

Funder

American Cancer Society Research Scholar

Indiana Drug Discovery Alliance

Vera Bradley Foundation

Indiana University

Lilly Endowment

Indiana University Pervasive Technology Institute

Indiana METACyt Initiative

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

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4. Phosphorylation of the Hippo pathway component AMOTL2 by the mTORC2 kinase promotes YAP signaling, resulting in enhanced glioblastoma growth and invasiveness;Artinian;J. Biol. Chem.,2015

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