From Discovery to Bedside: Targeting the Ubiquitin System
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference155 articles.
1. Discovery of 4-((3′R,4′S,5′R)-6″-Chloro-4′-(3-chloro-2-fluorophenyl)-1′-ethyl-2″-oxodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indoline]-5′-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development
2. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes;Altun;Chem. Biol.,2011
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4. Targeting the AAA ATPase p97 as an approach to treat cancer through disruption of protein homeostasis;Anderson;Cancer Cell,2015
5. Structural characterization of the interaction of Ubp6 with the 26S proteasome;Aufderheide;Proc. Natl. Acad. Sci. U S A,2015
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