Activation of STAT3/HIF-1α/Hes-1 axis promotes trastuzumab resistance in HER2-overexpressing breast cancer cells via down-regulation of PTEN-Reference-Cited by-同舟云学术

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Activation of STAT3/HIF-1α/Hes-1 axis promotes trastuzumab resistance in HER2-overexpressing breast cancer cells via down-regulation of PTEN

Published:2017-08 Issue:8 Volume:1861 Page:1970-1980
ISSN:0304-4165
Container-title:Biochimica et Biophysica Acta (BBA) - General Subjects
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - General Subjects

Author:

Aghazadeh Safiyeh,Yazdanparast Razieh

Funder

Research Council of University of Tehran

Iran National Science Foundation

National Institute of Genetic Engineering and Biotechnology

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference47 articles.

1. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications;Sørlie;Proc. Natl. Acad. Sci. U. S. A.,2001

2. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene;Slamon;Science,1987

3. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis;Moasser;Oncogene,2007

4. The ErbB2 signaling network as a target for breast cancer therapy;Badache;J. Mammary Gland Biol. Neoplasia,2006

5. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer;Vogel;J. Clin. Oncol.,2002

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