Fluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg2+ to the second metal binding site-Reference-Cited by-同舟云学术

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Fluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg2+ to the second metal binding site

Published:2016-03 Issue:3 Volume:1860 Page:569-575
ISSN:0304-4165
Container-title:Biochimica et Biophysica Acta (BBA) - General Subjects
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - General Subjects

Author:

Oppegard Lisa M.,Schwanz Heidi A.,Towle Tyrell R.,Kerns Robert J.,Hiasa Hiroshi

Funder

National Institutes of Health

National Institutes of Health Predoctoral Traineeship in Biotechnology

American Foundation for Pharmaceutical Education

American Chemical Society Division of Medicinal Chemistry Predoctoral Fellowship

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference47 articles.

1. DNA topoisomerases: structure, function, and mechanism;Champoux;Annu. Rev. Biochem.,2001

2. Cellular roles of DNA topoisomerases: a molecular perspective;Wang;Nat. Rev. Mol. Cell Biol.,2002

3. DNA topoisomerase II and its growing repertoire of biological functions;Nitiss;Nat. Rev. Cancer,2009

4. All tangled up: how cells direct, manage and exploit topoisomerase function;Vos;Nat. Rev. Mol. Cell Biol.,2011

5. The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks;Bates;Nucleic Acids Res.,2011

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