Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket-Reference-Cited by-同舟云学术

Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket

Published:2023-04 Issue:4 Volume:1867 Page:130313
ISSN:0304-4165
Container-title:Biochimica et Biophysica Acta (BBA) - General Subjects
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - General Subjects

Author:

Thanassoulas Angelos,Vassilakopoulou Vyronia,Calver Brian L.,Buntwal Luke,Smith Adrian,Lai Christopher,Kontogianni Iris,Livaniou Evangelia,Nounesis George,Lai F. Anthony,Nomikos Michail

Funder

Qatar University

Qatar National Library

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference38 articles.

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3. Thermodynamics of Calcium binding to the Calmodulin N-terminal domain to evaluate site-specific affinity constants and cooperativity;Beccia;J. Biol. Inorg. Chem.,2015

4. Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor);Balshaw;J. Biol. Chem.,2001

5. Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure;Yang;Circ. Res.,2014

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1. Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function;Journal of Cellular Biochemistry;2024-06-30

2. Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket;International Journal of Molecular Sciences;2023-10-26

3. Sphingosylphosphorylcholine alleviates pressure overload-induced myocardial remodeling in mice via inhibiting CaM-JNK/p38 signaling pathway;Acta Pharmacologica Sinica;2023-10-13