Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding-Reference-Cited by-同舟云学术

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Published:2016-11 Issue:11 Volume:1860 Page:2537-2552
ISSN:0304-4165
Container-title:Biochimica et Biophysica Acta (BBA) - General Subjects
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - General Subjects

Author:

Huerta Carlos,Jiang Xin,Trevino Isaac,Bender Christopher F.,Ferguson Deborah A.,Probst Brandon,Swinger Kerren K.,Stoll Vincent S.,Thomas Philip J.,Dulubova Irina,Visnick Melean,Wigley W. Christian

Funder

Industrial Macromolecular Crystallography Association

Hauptman-Woodward Medical Research Institute

U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference56 articles.

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3. A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders;Kim;Mutat. Res.,2010

4. Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress;Dinkova-Kostova;Proc. Natl. Acad. Sci. U. S. A.,2005

5. RTA 408, a novel synthetic triterpenoid with broad anticancer and anti-inflammatory activity;Probst;PLoS One,2015

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